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Urate bladder stones are most commonly the result of a genetic abnormality in breeds such as dalmatians. Other causes include liver diseases such as portosystemic shunts. The most common signs that a dog has bladder stones are difficulty urinating and blood in the urine. Strategies for treating urate bladder stones in dogs include medical dissolution and removal. Dogs that have experienced urate bladder stones will often be fed a therapeutic diet for life. Dogs with liver disease will need to be treated appropriately prior to addressing urate bladder stone management.
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Urinalysis is an important part of any comprehensive workup or health screen as it provides information on the urinary system including the kidneys and bladder and also can support diagnosis of metabolic disease such as diabetes mellitus. Urine collection methods include cystocentesis, catheterization, or mid-stream free flow, each of which has their own pros and cons. Urine samples are assessed using the following parameters: appearance (color and turbidity), concentration assesses how the urine has been concentrated by the kidneys, urine dipsticks (assess pH, glucose, protein, blood, ketones, urobilinogen, and bilirubin), and microscopic exam of sediment (may reveal the presence of abnormal cells including red blood cells, white blood cells, and tissue cells or crystals). A cytological preparation of sediment may be recommended to look at tissue cells in more detail.
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Urinary incontinence (UI) is the loss of voluntary control of urination. The most common clinical sign is pooling or spotting of urine underneath your dog when it is sleeping or relaxed. Urinary incontinence is diagnosed based on clinical signs, medical history, blood tests, and urine tests. Bladder X-rays and ultrasounds are often performed to search for bladder stones or other abnormalities affecting urine storage and outflow. Treatment will be based on your pet's specific diagnosis. Medications that increase urethral sphincter tone such as phenylpropanolamine (PPA), or hormone replacements such as estrogen or diethylstilbestrol (DES), are commonly used alone or in combination. In general, the prognosis is good.
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While urinary tract disorders are common in cats, urinary tract infections (UTIs) are fairly uncommon. Cats with UTIs tend to have the following signs: frequently passing small amounts of urine, straining to urinate, blood in the urine, crying out or whining while urinating, licking their genitals, and urinating outside the litterbox. Generally, a UTI occurs when bacteria travel up the urethra and into the bladder. If your cat presents to your veterinarian with urinary signs, your veterinarian will first perform a urinalysis. Once the culture and sensitivity results are received, an appropriate antibiotic will be prescribed. Older female cats and cats with certain health conditions may be predisposed.
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Urinary tract infections (UTIs) are fairly common in dogs. Dogs with UTIs tend to have the following signs: attempting to urinate frequently when they go outside, straining to urinate, blood in the urine, crying out or whining while urinating, licking their genitals, and a break in house training. Generally, a UTI occurs when bacteria travel up the urethra and into the bladder. If your dog presents to your veterinarian with urinary signs, your veterinarian will first perform a urinalysis. Once the culture and sensitivity results are received, an appropriate antibiotic will be prescribed. Older female dogs and dogs with certain health conditions may be predisposed.
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Tumors of the urinary tract may present anywhere from the kidneys to the tip of the urethra. Tumors of the bladder are most common in the dog whereas tumors involving the kidneys are more prevalent in cats. Unfortunately, many tumors of the urinary tract are malignant and treatment options may be limited. Surgery is possible in select cases. Medical treatment may be beneficial in cases where surgery is not possible.
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Cortisol is a stress hormone that is excreted from the body in the urine. Creatinine is a product of muscle metabolism and is normally lost in the urine at a relatively steady rate. The ratio of creatinine to cortisol in the urine can be used to account for the effect of urine concentration on cortisol measurements. Urine cortisol/creatinine ratio is usually evaluated in animals suspected of having Cushing's disease. This test involves the collection of a single urine sample, taken first thing in the morning.
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The presence of protein in urine is called proteinuria, and it may indicate that the kidneys are not working properly. In some situations, proteinuria may even be a sign of kidney failure; however, bleeding or inflammation in the urinary system is a far more common cause. Your veterinarian may recommend further testing if the urinalysis reveals inflammation or bleeding.
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The urine protein/creatinine (UPC) ratio is a test that measures how much protein is being lost through the kidneys. The UPC measures whether protein excretion is greater than expected when compared to the excretion of creatinine. Before the UPC ratio can be interpreted, two other measures of kidney function should be taken: blood urea nitrogen (BUN) and serum creatinine.
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Urine scalding of grass is due to the nitrogen in your dog's urine. Nitrogen is a by-product of protein breakdown and is a normal component of your dog's urine. A bit of nitrogen acts as a food source for plants, such as in fertilizer, but too much will burn the grass. It is not related to the pH of the urine. You can reduce burning by encouraging your dog to drink water to dilute the urine, thereby diluting the nitrogen. It is not recommended to restrict protein from your dog. Watering the grass after your dog urinates or training your dog to urinate in specific locations away from your lawn are the only ways to prevent the problem.
