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  • Dermatomyositis is hereditary, immune-mediated disease of the skin muscles and blood vessels affecting primarily collies, Shetland Sheepdogs and mixes of these breeds. Other breeds can experience similar disease. Signs are usually first recognized in puppies but can present in young adulthood. Signs include: skin lesions (crusty erosions, patchy alopecia or ulcers) around the eyes, lips, face, ear flaps or tail tip, foot pad lesions; atrophy of chewing muscles or difficulty chewing; stiff gait and megaesophagus in severely affected dogs. Skin biopsies are diagnostic. Treatment involves treating secondary bacterial infections, reducing sun exposure, EFAs, and immunomodulatory medications including tetracycline, niacinamide, pentoxifylline, cyclosporine and corticosteroids. Prognosis varies depending on severity.

  • Testing for diabetes includes confirming hyperglycemia and glucosuria while looking for other conditions by taking a complete blood count (anemia, infection), biochemistry profile (hepatic disease, pancreatitis), and a urinalysis (urinary tract infection). Monitoring includes regular glucose curves and additional exams and testing based on the pet owner's monitoring of their cat's clinical signs at home. Urine glucose testing and fructosamine are sometimes used in diabetic monitoring and urine testing for infection may be recommended.

  • Testing for diabetes includes confirming hyperglycemia and glucosuria while looking for other conditions by taking a complete blood count (anemia, infection), biochemistry profile (hepatic disease, pancreatitis), and a urinalysis (urinary tract infection). Monitoring includes regular glucose curves and additional exams and testing based on the pet owner's monitoring of their dog's clinical signs at home. Urine glucose testing and fructosamine are sometimes used in diabetic monitoring and urine testing for infection may be recommended.

  • Diabetes insipidus is rare in cats and is characterized by excessive drinking and the production of enormous volumes of extremely dilute urine. Despite drinking large volumes of water, the cat can become dehydrated from urinating so much. Increased drinking and urination are common signs of several other health conditions, so it is essential that several diagnostic tests be performed to diagnose diabetes insipidus. While the condition is rarely curable, it is usually successfully controlled.

  • Diabetes insipidus results in excessive drinking and urination. As many conditions cause these signs, a number of diagnostic tests including bloodwork and urinalysis need to be performed to rule out other causes. After more common causes are ruled out, a modified water deprivation test can confirm disease and an MRI or therapeutic trial can be performed. Diabetes insipidus results from reduced production of ADH from the brain or reduced sensitivity to ADH in the kidney. Treatment depends on the cause of the disease either replacing the lack of ADH with a synthetic replacement or using a hydrochlorothiazide and a low salt diet to decrease urine production.

  • Diabetes is an inability of the body to regulate blood sugar caused by an abnormality of the pancreas. It is the second-most common endocrine disease in cats. It causes increased thirst, urination, appetite, and weight loss. Cats most commonly have type 2 diabetes, caused by decreased insulin production or insulin resistance, and it is often associated with obesity. Diabetes is diagnosed by measuring increased levels of glucose in the urine and blood. Diabetes treatment includes insulin injections and dietary changes. Changes in blood sugar must be monitored regularly.

  • Diabetes is an inability of the body to regulate blood sugar caused by an abnormality of the pancreas. It causes increased thirst, urination, appetite, and weight loss. Most dogs have type 1 diabetes, caused by total or near destruction of the insulin-producing cells, and insulin injections are required for treatment. Diabetes is diagnosed by measuring increased levels of glucose in the urine and blood. Diabetes treatment includes insulin injections and dietary manipulation with regular blood sugar monitoring. Financial costs can be high during the regulation period, or if a complication arises, and twice-daily insulin injections are a lifelong commitment.

  • Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body's response to the injections needs to be regularly monitored using an at-home glucometer or continuous glucose monitoring system. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet.

  • Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body's response to the injections needs to be regularly monitored using an at-home glucometer or continuous glucose monitoring system. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet.

  • New medications can help regulate blood glucose levels in cats, including once-daily oral medications bexagliflozin (Bexacat) and velagliflozin (Senvelgo). Cats in the initial stages of DM may benefit most from oral diabetes treatments. This article discusses how these medications work, potential risks, and monitoring required.

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