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Stem cells are unspecialized cells that are capable of renewing themselves though cell division. Under certain conditions, they can become a specific tissue or organ cell. Stem cell therapy commonly refers to the process of placing stem cells from the body into diseased or damaged tissues, such as a torn ligament in the knee or perhaps an arthritic joint. This process is often referred to as regenerative medicine. Adult stem cells are capable of repair and regeneration of various tissues because they have the potential to differentiate into specialized cells of an organ. The most common use of stem cell therapies has been in the treatment of osteoarthritis in dogs and cats. Currently, there are no current guidelines with respect to stem cell therapy. Stem therapy should only be performed by a veterinarian with special training, who understands the benefits and limits of this therapy. It is important to have realistic expectations as positive outcomes cannot be guaranteed.
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This handout discusses the use of corticosteroid (such as prednisone or dexamethasone) in the dog. Reasons for use as well as the common short-term and long-term side effects of these drugs are outlined, along with strategies to avoid these effects.
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Stomach tumors are uncommon in dogs and cats. There are many kinds, including leiomyosarcomas, lymphomas, adenocarcinomas, mast cell tumors, fibrosarcomas, plasmacytomas, gastrointestinal stromal tumors (GISTs), and carcinoids (all malignant); and leiomyomas, adenomatous polyps, and adenomas (benign). Most tumors are malignant. Stomach tumors are more prevalent in older animals, males, and certain breeds. The signs of stomach tumors include chronic vomiting, inappetence, lethargy, and weight loss. Sometimes tumor ulceration will cause anemia. Paraneoplastic syndromes are possible with the muscle tumors. Stomach tumors may be diagnosed with imaging, endoscopy, or surgery, with a biopsy. Treatment may involve surgery, chemotherapy, or radiation therapy.
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Strokes are rare in dogs. Some causes include a blood clot such as a thrombus or embolus that lodges in a cerebral blood vessel, cerebral bleeding from trauma, or a blood clotting disorder; however, the cause is often unknown. Signs of a stroke are variable depending on the regions of the brain affected and the degree and duration of blood and oxygen deprivation. Magnetic resonance imaging is the ideal diagnostic test for diagnosing a stroke. Treatment is complex and there is no guarantee of complete success. Your veterinarian will help you assess progress and plan remedial action.
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Struvite bladder stones are one of the more common bladder stones found in dogs. Struvite bladder stones usually form as a complication of a bladder infection caused by bacteria, and if the urine becomes exceptionally concentrated and acidic. The most common signs that a dog has bladder stones are blood in the urine (hematuria) and straining to urinate (dysuria). There are three primary treatment strategies for struvite bladder stones: 1) feeding a special diet to dissolve the stone(s), 2) non-surgical removal by urohydropropulsion (flushing out the stones) and 3) surgical removal. Dogs that have experienced struvite bladder stones will often be fed a therapeutic diet for life.
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Stud tail, or tail gland hyperplasia, is a condition in which the oil glands near the base of the tail enlarge. This condition causes hair loss, excess accumulation of oils in the skin and on the fur, plugged hair follicles, and secondary infections. It is most common in intact male dogs, as these glands are under hormonal control, but any dog can be affected. Other hormonal imbalances and skin disorders can also cause this problem. Prognosis is generally good, especially if the underlying cause can be identified and controlled.
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Administering supplemental fluids can benefit dogs with a variety of medical conditions. Giving injections is outside the comfort zone for almost anyone outside the medical profession; however, subcutaneous fluid administration is not nearly as difficult as it sounds. Your veterinary healthcare team will provide you with all the equipment that you will need to administer fluids to your dog. They will go through the steps with you in person. Do not use the fluid bag if cloudiness or discoloration develops in the fluids.
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Many pets initially resist having their claws trimmed. This is partly because their paws are sensitive and partly because they are uncomfortable being restrained for the procedure. By taking the time to do some gentle, systematic training and conditioning, you can teach your pet to relax and accept nail trims as part of their regular health maintenance program.
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Many pets are sensitive to being restrained for grooming. With slow progress and positive rewards, your pet can learn to accept or even enjoy having their teeth cleaned.
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Sucralfate is given by mouth and is used off-label to treat ulcers and erosions in the mouth, esophagus, stomach, and upper small intestine. Give as directed. Side effects are uncommon but may include constipation. Do not use in pets that are allergic to this medication. If a negative reaction occurs, please call your veterinarian.
