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Mast cells are a type of white blood cell that plays a large role in allergic response through degranulation. Mast cell tumors (MCT) can occur in the skin, spleen, or gastrointestinal tract of cats. Their cause is unknown; however, many affected cats show a genetic mutation in the KIT protein involved in replication and cell division. Cutaneous MCTs most often appear as hard pale/white plaques or nodules, often around the head and they may be itchy. Splenic MCTs cause decreased appetite, weight loss, and vomiting. Intestinal MCTs may cause GI upset and bloody stools, and a mass may be palpable. Diagnosis is typically achieved via fine needle aspirate although histopathology can be used. Treatment usually requires surgical removal of the masses or the spleen. Sometimes, chemotherapy or radiation is needed.
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Mastitis is a term used to describe inflammation of a mammary gland (breast), most frequently seen in the postpartum period after a cat gives birth. In most cases, mastitis is caused by a bacterial infection. Trauma to the nipple or teat canal can allow bacteria to enter, traveling up into the mammary gland and creating a bacterial infection. Most cats with mastitis can be treated on an outpatient basis with oral antibiotics and pain medications, though severe cases may require hospitalization or surgery.
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Meclizine is used off label and given by mouth in the form of a tablet to treat and prevent motion sickness and vomiting in dogs, cats, and small mammals. The most common side effect is sedation and sleepiness. Do not use in pets that are allergic to it. It should be used with caution in pets with concurrent prostate enlargement, bladder obstruction, heart failure, certain types glaucoma, or certain gastrointestinal obstructions. If a negative reaction occurs, please call your veterinary office.
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For most cats, a visit to the veterinarian is an overwhelming experience. If your cat’s veterinary appointment is for a routine wellness examination, your veterinarian may prescribe a sedative or antianxiety medication. Natural medicines, also known as complementary therapies, cover a wide range of products including herbs, nutraceuticals, supplements, and homeopathic remedies and may be beneficial in treating your anxious cat. Products such as Feliway® and Rescue Remedy® are examples of natural therapies that may be helpful in reducing your cat’s stress. One of the most important ways to decrease your cat’s anxiety level is to remain calm and relaxed during the visit as this will help reassure your cat that she is safe.
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Medicinal mushrooms are given by mouth and are used over the counter (and under veterinary supervision) to supplement the treatment of cancer and other conditions. Give as directed by your veterinarian. Side effects may include stomach upset, diarrhea, dizziness, and skin rash. Do not use in pets that are allergic to mushrooms, and use cautiously in pets that are pregnant, nursing, or have diabetes, clotting disorders, low blood pressure, immune-mediated disorders, liver problems, or kidney disease. If a negative reaction occurs, please call your veterinary office.
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Medroxyprogesterone acetate is given by mouth or injection and is used off label to treat reproductive conditions, sexual behaviors, and certain types of dwarfism and alopecia. Give this medication as directed by your veterinarian. Common side effects include increased appetite, increased thirst, weight gain, sleepiness, or changes in personality. Do not use in pets that are allergic to it, pets with diabetes or uterine bleeding, or prior to puberty, during pregnancy, 1-2 months after a heat cycle, or to treat false-pregnancy. If a negative reaction occurs, please call your veterinary office.
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If the nerves to the colon do not function normally, the muscles of the colonic wall will not contract properly. The muscles then become stretched and the colon enlarges in diameter. Rather than being pushed into the rectum in a normal manner, fecal material accumulates in the distended colon, resulting in severe constipation called obstipation. This massive enlargement of the colon and the resulting constipation is called megacolon. Megacolon is often treatable using a medical approach but some cases require surgical intervention called subtotal colectomy.
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Megaesophagus is a disorder in which the esophagus dilates and loses motility. When esophageal motility is decreased or absent, food and liquid accumulate in the esophagus and have difficulty getting into the stomach. Regurgitation is the most common sign of megaesophagus. Weight loss or failure to gain weight, as well as aspiration pneumonia, are also common signs. Treatment is focused on managing the symptoms.
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Megestrol acetate is given by mouth in the form of a tablet or liquid and is used in dogs or off label in cats to postpone the heat cycle or to treat false pregnancy. It can also be used off label in male dogs to treat prostatic hypertrophy. It should not be used in pregnant pets or pets with uterine disease, diabetes, or breast tumors.
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Melanomas are cancerous growths of the cells responsible for pigmentation of the skin. They can develop anywhere on the body but those on the toes carry the highest chance for malignancy. They may be painful and you may notice your pet licking at the affected area. Surgery is often the treatment of choice and may be followed up with radiation or chemotherapy.
