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  • Pituitary macroadenomas are large tumors of the pituitary gland that are either functional (secrete hormones) or non-functional (do not secrete hormones). The clinical signs depend on the type of macroadenoma, though become severe over time in either case. Diagnosis requires specialized CT or MRI imaging. This handout explains the effects of macroadenomas in cats and the treatment options available.

  • Plasma cell tumors develop as a result of dysregulated production of plasma cells and are relatively uncommon in dogs and cats. Some plasma cell tumors are benign and the most common locations for these tumors are the head, feet, lips, mouth, and ears. The treatment of choice for benign plasma cell tumors is surgical removal, with little to no recurrence if completely excised. Conversely, multiple myeloma is a very malignant cancer that is usually treated with chemotherapy.

  • Some cats do not seem to know their strength and do not recognize that they are causing pain to their play partners. Accidental bites and scratches can be painful and cause infection, so it is important to find ways to play safely. With training, you may be able to use a verbal cue to redirect your cat if he becomes overly aroused during play.

  • Pleural effusion refers to the abnormal accumulation of fluid within the chest cavity. The fluid is not found within the lungs, but instead within the pleural sac, essentially meaning the lungs are floating in a chest that is full of fluid. Several conditions can cause pleural effusion, including chylothorax, heart failure, and tumors in the lungs or chest wall. Immediate treatment often requires oxygen support and the removal of the excess fluid by thoracocentesis, which can also then be tested to diagnose the cause of the pleural effusion. Treatment and prognosis vary depending on the underlying cause of the pleural effusion.

  • Polycystic Kidney Disease (PKD) is an inherited condition that causes multiple cysts (fluid pockets) in the kidneys. Persian cats and breeds with Persian bloodlines are most commonly affected. The clinical signs, diagnosis, genetic testing, and treatment options are explained in this handout.

  • Polysulfated glycosaminoglycan is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.

  • When your cat comes home after an operation, special care must be taken to ensure he remains indoors with restricted activity and cannot lick or chew at his incision site. Monitor your cat for abnormal signs and contact your veterinarian if any are observed.

  • This handout explains post-vaccination sarcomas (also called injection-site sarcomas) in cats. They are a rare consequence of vaccine injections (and other drugs or materials) that can cause a very aggressive form of cancer at the site of the injection. The incidence of this condition, as well as precautions you and your veterinarian can take, are highlighted.

  • Feline poxvirus is a relative of the human smallpox virus seen mainly in Asia, Europe, and England. It causes skin lesions around the head, neck, and forelimbs, such as ulcerations, scabs, or abscesses. Cats often recover on their own with no further symptoms unless they are immunocompromised. There is no specific treatment or vaccine. Antibiotics may be used to control secondary infections. The virus can be transmitted to humans but can be significantly reduced by basic hygiene precautions.

  • Prazosin is given by mouth and is used to reduce urinary sphincter tone to relax the bladder and allow easier urination in dogs and cats. It may also be used as a treatment for congestive heart failure, systemic hypertension, or pulmonary hypertension in dogs. Give as directed. Common side effects include lethargy, vomiting, diarrhea, nausea, and constipation. This medication should be used with caution in pets with kidney disease or other conditions that cause low blood pressure, as well as in MDR1-positive dogs. If a negative reaction occurs, contact your veterinarian.

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