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  • Butorphanol is a partial opiate agonist/antagonist that is used as an analgesic, pre-anesthetic, antitussive, or antiemetic. The injectable form is used subcutaneously, intramuscularly, or intravenously, and the tablet is given by mouth. Side effects include sedation, ataxia, anorexia, or rarely diarrhea. Caution should be used in pets with liver or kidney disease, Addison's disease, head trauma, or other CNS dysfunction, or in geriatric or severely debilitated patients.

  • Pet owners may not realize that caffeine can be harmful to their pets. They also may not know that many foods and drinks in their cupboards contain caffeine. This particular chemical can be toxic for both cats and dogs.

  • These two conditions are the result of calcium being deposited within the skin. They are usually of minor significance in young dogs and cats but can indicate serious underlying diseases in older pets. This handout describes the different types of calcinosis circumscripta and cutis and associated causes, clinical signs, and treatments.

  • Calcitriol is used off label and is given by mouth or injection to treat low blood calcium levels associated with low parathyroid hormone, as well as chronic kidney disease, certain cancers, and certain skin diseases. Side effects are uncommon if the dose is appropriate.

  • Calcium acetate is given off label and by mouth to treat elevated blood phosphorus levels, especially due to kidney disease. Side effects may include nausea or stomach upset. This medication should not be used in pets that are allergic to it or have high blood calcium levels. If a negative reaction occurs, please call your veterinary office.

  • Calcium carbonate + chitosan (brand name Epakitin®) is a phosphorus binder and calcium supplement. It is used to treat high blood phosphorus levels in cats and dogs with chronic kidney disease and to treat low blood calcium levels in cats, dogs, and other species.

  • Calcium oxalate bladder stones are composed of a mineral called calcium oxalate. Cats are more likely to develop oxalate stones when their urine contains high levels of calcium and oxalate. Additionally, a low urine pH promotes the formation of oxalate stones. Bladder stones can cause significant inflammation and irritation of the bladder wall. Signs may include frequent urination, straining to urinate, blood in the urine, and urinating outside of the litterbox. Male cats especially are at risk of a life-threatening urinary obstruction. Treatment options and prognosis are discussed.

  • Calcium supplements are given by mouth or injection and are used on and off label and over the counter to treat low blood calcium levers in many species. Give as directed by your veterinarian. Side effects are uncommon but may include constipation. Do not use in pets with high blood calcium. If a negative reaction occurs, please call your veterinary office.

  • Calendula is given directly on the skin or by mouth and is used off label and over the counter to treat skin inflammation or gastrointestinal ulcers. Give as directed by your veterinarian. Side effects are uncommon but may include skin or stomach irritation. Do not use in pets that are allergic to it or that are pregnant. If a negative reaction occurs, please call your veterinary office.

  • Cannabidiol, also known as CBD, is a naturally occurring cannabinoid (a compound found in the Cannabis plant), which is used as an analgesic (pain reliever) and anticonvulsant. It is used to treat osteoarthritic pain and to help control seizures in dogs and other species. Cannabidiol should only be given under direction of a veterinarian. It is used “off label” or “extra label” in animals.

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