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Dogs + Treatment

  • This handout outlines the use of disease-modifying osteoarthritis drugs (DMOADs) in dogs, specifically the use of polysulfated glycosaminoglycans (PSGAGs). The rationale for their use, and their dosing regimen are explained.

  • Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.

  • Mastitis is a term used to describe inflammation of a mammary gland. In most cases, mastitis is caused by a bacterial infection. Trauma to the mammary gland, or prolonged periods of milk accumulation without milk removal, can lead to inflammation within the mammary gland. Most dogs with mastitis can be treated on an outpatient basis with oral antibiotics and pain medications, though severe cases may require hospitalization or surgery.

  • Silymarin is an over-the-counter nutritional supplement that is used off-label and is given by mouth to treat liver and cancer conditions. Give as directed. Side effects are uncommon but may include vomiting or diarrhea. Do not use it in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.

  • Pain research has advanced suggesting that a more appropriate choice for managing the chronic pain of OA is multi-modal therapy. Non-steroidal anti-inflammatory drugs are just one of the options leveraged for multi-modal OA management. These include joint supplements, nutraceuticals, nutrition, adjunctive medicines, physical medicine, and changes to the home environment. Every multi-modal treatment plan is tailored to meet the needs of the individual patient and then adjusted as treatment progresses. Once a full multi-modal pain management plan is in place, your veterinarian may be able to lower the dose of NSAID to minimize the risk of an adverse event, and to reserve a full therapeutic dose for any acute inflammatory pain event.

  • Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.

  • Supportive braces can help dogs with many orthopedic conditions, including skeletal deformities, carpal hyperextension, and cruciate ligament disease. It is important to have any brace properly fitted to avoid complications. Braces are not considered equivalent to surgery for cruciate ligament disease.

  • Many dogs will instinctively hide their pain as a survival mechanism which in the past, led well-meaning experts to presume that dogs did not feel pain the same way humans do. Although the signs may be subtle, careful observation of a dog’s everyday behaviors will often reveal pain when it is present. These signs may include changes in behavior, mobility, and appetite. Common pain medications include NSAIDs, opioids, and other therapeutics. Your veterinarian will choose the appropriate drugs based on your dog’s specific needs.

  • Penetrating wounds can look minor on the surface but may cause severe injury below the skin. A thorough assessment requires sedation or anesthesia and surgery may be required to address the extent of the injury. This handout outlines first aid steps a pet owner can take while transporting their injured pet to the veterinary hospital.

  • Pneumothorax is an accumulation of air outside the lungs, but inside the chest wall. The air outside the lung prevents the lungs from inflating normally, and can lead to lung collapse. There are several variations of pneumothorax.



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