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  • Methylsulfonylmethane is given by mouth and is used over the counter and off label to treat inflammatory conditions such as arthritis. Give as directed by your veterinarian. Side effects are uncommon but may include stomach upset, restlessness, or tiredness. Do not use in pets that are allergic to it or that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.

  • Metoclopramide is given by mouth or injection and is used off-label to treat gastrointestinal motility disorders, nausea, and vomiting in dogs, cats, and other animals. Give as directed. Side effects are uncommon but may include restlessness, hyperactivity, muscle twitches, drowsiness, and increased urination. Do not use in pets with intestinal blockage or bleeding, pseudopregnancy, pheochromocytoma, or a history of seizures or head trauma. If a negative reaction occurs, contact your veterinarian.

  • Metronidazole is given by mouth or injection and is used off-label to treat certain anaerobic bacterial and protozoal infections and gastrointestinal conditions in dogs, cats, and other animals. Give as directed. Side effects may include nausea, vomiting, diarrhea, regurgitation, decreased appetite, tiredness, and drooling. Do not use in pets that are allergic to it, are debilitated, or are pregnant or nursing. If a negative reaction occurs, contact your veterinarian.

  • Mexiletine is given by mouth and is used off label to treat abnormal heart rhythms and muscle disorders in dogs. Common side effects include stomach upset such as vomiting, trembling, or dizziness. Do not use in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Miconazole otic is an antifungal used in the treatment of external ear infections (otitis externa) caused by fungal organisms in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. Miconazole otic comes in ointment or liquid drop suspension forms that may be specially compounded.

  • Miconazole topical is an antifungal used in the treatment of skin infections caused by yeast in cats and dogs. It may be used “off-label” or “extra label” for other conditions and in other animals. It may be specially compounded and/or combined into a formulation with other medications. Miconazole topical comes in a variety of forms.

  • If microalbuminuria is detected, your veterinarian will likely recommend further testing to look for hidden disease. The choice of tests may vary but could include routine blood tests and urinalysis (see handouts “Complete Blood Count”, “Serum Biochemistry”, and “Urinalysis” for more information). If there is no evidence of underlying illness, then regular check-ups every 3-6 months, including microalbuminuria testing, may be recommended to monitor your dog’s health status and to watch for any changes.

  • The purpose of pet microchips is to provide permanent identification. Microchips are tiny, about the size of a grain of rice, and contain a unique identification number. They are inserted with a needle under the skin between the shoulder blades. A microchip reader detects the electronic code embedded in the chip and displays the identification number on its screen. The registration database is then checked for this identification number (either online or by telephone), and the pet owner's contact information is retrieved. A microchip is the most reliable way to reunite lost pets with their owners and may also be required for international travel.

  • Midazolam is a benzodiazepine used for its sedative, anti-anxiety, and muscle relaxant properties. It is primarily used as a sedative before surgery and to stop seizures. It is used “off label” or “extra label” in animals. This medication is a controlled substance primarily given via injection by your veterinary team, though it may be prescribed to your pet for intranasal or intrarectal administration at home.

  • Milbemycin oxime is a heartworm disease preventive and treats internal parasites in dogs and cats (e.g., hookworms and roundworms). It is also used off label to treat infestations in dogs. Milbemycin is given by mouth with a flavored oral tablet.