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  • Some cats do not seem to know their strength and do not recognize that they are causing pain to their play partners. Accidental bites and scratches can be painful and cause infection, so it is important to find ways to play safely. With training, you may be able to use a verbal cue to redirect your cat if he becomes overly aroused during play.

  • Pleural effusion refers to the abnormal accumulation of fluid within the chest cavity. The fluid is not found within the lungs, but instead within the pleural sac, essentially meaning the lungs are floating in a chest that is full of fluid. Several conditions can cause pleural effusion, including chylothorax, heart failure, and tumors in the lungs or chest wall. Immediate treatment often requires oxygen support and the removal of the excess fluid by thoracocentesis, which can also then be tested to diagnose the cause of the pleural effusion. Treatment and prognosis vary depending on the underlying cause of the pleural effusion.

  • Pneumothorax is an accumulation of air outside the lungs, but inside the chest wall. The air outside the lung prevents the lungs from inflating normally, and can lead to lung collapse. There are several variations of pneumothorax.

  • Polycystic Kidney Disease (PKD) is an inherited condition that causes multiple cysts (fluid pockets) in the kidneys. Persian cats and breeds with Persian bloodlines are most commonly affected. The clinical signs, diagnosis, genetic testing, and treatment options are explained in this handout.

  • Polycythemia vera is a rare disease of dogs and cats in which too many red blood cells are produced by the bone marrow. The blood becomes thick and has difficulty moving through the small blood vessels. Your pet may feel tired, sluggish, and weak. Polycythemia is a potentially fatal disease, but if discovered early enough, treatment may be possible. If left untreated, polycythemia vera can affect the heart.

  • Polyethylene glycol is an off-label laxative used to treat constipation and empty the colon in preparation for procedures such as colonoscopy. The most common side effects are diarrhea, flatulence, and abdominal cramping. Do not use it in pets that are allergic to it or in pets with an intestinal blockage/obstruction.

  • Polymyxin B/miconazole/prednisolone otic (brand name Surolan), is a combination antibacterial (polymyxin B), antifungal (miconazole), and anti-inflammatory steroid (prednisolone) ear drop medication. It is used to treat ear infections in cats and dogs. It is used “off label” or “extra-label” in species other than cats and dogs and to treat conditions other than ear infections. Polymyxin B/miconazole/prednisolone otic comes in an otic suspension form.

  • Polysulfated glycosaminoglycan is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.

  • Ponazuril is given by mouth and is used on and off label to treat protozoal parasites in a variety of animal species. Side effects are uncommon but may include soft stools. Do not use in pets that are allergic to it. Ponazuril should be used cautiously in pregnant or lactating pets, and dogs with/susceptible to dry eye (keratoconjunctivitis sicca/KCS).

  • When your cat comes home after an operation, special care must be taken to ensure he remains indoors with restricted activity and cannot lick or chew at his incision site. Monitor your cat for abnormal signs and contact your veterinarian if any are observed.