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Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.
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Lysosomal storage diseases are a rare collection of conditions that are inherited. Many of them are more prevalent in certain breeds and are seen in the first few months of life. Clinical signs vary depending on the type of disease, but commonly include failure to thrive, incoordination, vision loss, and seizure. Prognosis is usually poor for long-term survival.
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Bacterial overgrowth is a condition of the small intestine resulting in increased numbers of bowel bacteria. The major concern with bacterial overgrowth is the development of a condition called small intestinal bacterial overgrowth. The bacteria cause damage to the surface of the bowel so digested food cannot be absorbed resulting in malabsorption of nutrients. Malabsorption and SIBO both result in diarrhea but with bacterial overgrowth the diarrhea is chronic. Many cases respond to long term antibiotics.
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Mast cells are a type of white blood cell that plays a large role in allergic response through degranulation. Mast cell tumors (MCT) can occur in the skin, spleen, or gastrointestinal tract of cats. Their cause is unknown; however, many affected cats show a genetic mutation in the KIT protein involved in replication and cell division. Cutaneous MCTs most often appear as hard pale/white plaques or nodules, often around the head and they may be itchy. Splenic MCTs cause decreased appetite, weight loss, and vomiting. Intestinal MCTs may cause GI upset and bloody stools, and a mass may be palpable. Diagnosis is typically achieved via fine needle aspirate although histopathology can be used. Treatment usually requires surgical removal of the masses or the spleen. Sometimes, chemotherapy or radiation is needed.
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Mast cell tumors are most common in the skin of dogs and may appear red, ulcerated, or swollen. They can be itchy and can fluctuate in size. Tumors can range from lower-grade, with minimal spread, to higher-grade, with a high risk of local invasion. Treatment usually involves surgical removal and may require supportive treatment including chemotherapy, radiation therapy, and therapy to target the mutation that instigated the tumor.
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Masticatory muscle myositis (MMM) is an immune system disorder in which the dog's immune system identifies the dog's own muscle tissue as foreign and attacks it.
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Mastitis is a term used to describe inflammation of a mammary gland (breast), most frequently seen in the postpartum period after a cat gives birth. In most cases, mastitis is caused by a bacterial infection. Trauma to the nipple or teat canal can allow bacteria to enter, traveling up into the mammary gland and creating a bacterial infection. Most cats with mastitis can be treated on an outpatient basis with oral antibiotics and pain medications, though severe cases may require hospitalization or surgery.
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Mastitis is a term used to describe inflammation of a mammary gland. In most cases, mastitis is caused by a bacterial infection. Trauma to the mammary gland, or prolonged periods of milk accumulation without milk removal, can lead to inflammation within the mammary gland. Most dogs with mastitis can be treated on an outpatient basis with oral antibiotics and pain medications, though severe cases may require hospitalization or surgery.
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If the nerves to the colon do not function normally, the muscles of the colonic wall will not contract properly. The muscles then become stretched and the colon enlarges in diameter. Rather than being pushed into the rectum in a normal manner, fecal material accumulates in the distended colon, resulting in severe constipation called obstipation. This massive enlargement of the colon and the resulting constipation is called megacolon. Megacolon is often treatable using a medical approach but some cases require surgical intervention called subtotal colectomy.
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Megaesophagus is a disorder in which the esophagus dilates and loses motility. When esophageal motility is decreased or absent, food and liquid accumulate in the esophagus and have difficulty getting into the stomach. Regurgitation is the most common sign of megaesophagus. Weight loss or failure to gain weight, as well as aspiration pneumonia, are also common signs. Treatment is focused on managing the symptoms.
