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  • Leishmaniasis is a disease caused by a protozoan parasite transmitted by sandflies and is most commonly seen in the Mediterranean, Middle East, and South and Central America. It has been reported in some parts of the United States. Clinical signs include hard skin nodules, weakness, decreased appetite, vomiting, diarrhea, and more. Diagnosis is based on travel history, clinical signs, and diagnostic testing. The goal of treatment is to resolve clinical signs. Prognosis is guarded to grave depending on the severity of the disease.

  • This handout discusses lens luxation in dogs. The lens is the transparent structure within the eye that focuses light on the retina. Lens luxation is when the support ligaments of the lens weaken or break, causing the lens to dislocate from its normal position. The various types, clinical signs, heredity of the condition, diagnosis, treatment, and prognosis are outlined.

  • Lenticular sclerosis is the term for a bluish, transparent haze that develops in the lens of the eye in middle-aged to senior dogs. Vision does not appear to be significantly affected. While the exact mechanism is poorly understood, it appears that the lens gradually becomes denser or harder with age. There is no specific treatment for lenticular sclerosis, nor is treatment necessary.

  • Leptospirosis is a bacterial disease of dogs and other mammals that primarily affects the liver or kidneys. The bacteria (Leptospira) that cause leptospirosis thrive in water. Infected or recovered carrier dogs may act as a source of the infection. Antibiotics such as penicillin, ampicillin, and amoxicillin, are reasonably effective against the acute stages of leptospirosis if started early, although most affected dogs require intensive care in the veterinary hospital. This disease can be transmitted to humans.

  • Levetiracetam is given by mouth or injection and is used off label to treat seizures and epilepsy. Give as directed by your veterinarian. Common side effects include sleepiness and incoordination in dogs and decreased appetite, incoordination, drooling, and sleepiness in cats. Do not use levetiracetam in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Levothyroxine is thyroid hormone replacement given by mouth in the form of a tablet or capsule. It is used to treat hypothyroidism and its use in cats and certain exotic animals is off label. This medication should not be used in pets with certain heart conditions, untreated Addison's disease, or hyperthyroidism.

  • Lick granuloma in dogs, also known as acral lick dermatitis, is a condition manifested as chronic licking of an area of skin, usually on the forelimbs. This condition is thought to be both physical and psychological in nature. While the condition can be frustrating to get under control, most cases of lick granulomas can be successfully treated if the owner is willing to pursue extended tests and treatments.

  • Crate training is useful in many situations, such as providing a safe place when home alone or unsupervised. Dogs that are calm in their crates experience less distress when they need to travel, visit the veterinary hospital, or stay at a boarding facility. Starting while your dog is young makes training easier, but even adult dogs can be trained to relax in a crate. If your dog shows signs of distress (e.g., prolonged vocalization, eliminating inside the crate, trying to escape, salivation) while using the training methods provided in this handout, consult your veterinarian.

  • Lincomycin is given by mouth or injection and is used on and off label to treat certain bacterial infections. Give as directed by your veterinarian. Common side effects include vomiting, diarrhea, or drooling. Do not use in pets that are allergic to it or similar drugs, in pets with a candida fungal infection, very young pets, or in rabbits, hamsters, guinea pigs, or horses. If a negative reaction occurs, please call the veterinary office.

  • Primary liver tumors in dogs and cats are rare. There are 4 types: hepatocellular tumors, bile duct tumors, neuroendocrine tumors, and sarcomas. These cancers can be massive, nodular, or diffuse in form. In dogs, most liver tumors are malignant, while in cats, most are benign. The signs of liver tumors range from being asymptomatic to having inappetence, fever, lethargy, and weight loss; and less commonly, nausea, vomiting and diarrhea; increased drinking and urination; and jaundice. Occasionally there are neurological signs, such as seizures. With tumor rupture and intrabdominal bleeding there may be weakness, collapse, and difficulty breathing. The diagnosis is based on history, clinical signs, exam findings, diagnostic imaging, and FNA or liver biopsy. A biopsy is best for a definitive diagnosis. Surgery is the treatment of choice for most primary liver tumors followed by chemotherapy. Chemoembolization is a newer treatment.

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