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Dexamethasone is given on and off label, by mouth or injection, to treat various inflammatory, autoimmune, and adrenal gland conditions. It can also be used off label as a diagnostic test. Common side effects include increased drinking, urination and/or appetite, dull/dry haircoat, weight gain, pot-bellied appearance, muscle weakness, panting, vomiting, or diarrhea. Do not use in pets that are allergic to it, have systemic fungal infections, diabetes, or stomach or intestinal ulcers, or are taking NSAIDs. It should not be used in rabbits or in surgical pets. If a negative reaction occurs, please call your veterinary office.
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Dexamethasone ophthalmic is a topical steroid medication used to treat inflammatory eye conditions in cats, dogs, rabbits, avian species, and other animals. Dexamethasone ophthalmic may be used alone or in combination with an antimicrobial. Dexamethasone ophthalmic comes in ointment and liquid drop form. Avoid use in animals with corneal ulcerations or corneal infections.
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Dexamethasone is used to test the level of cortisol hormone in the body. Injection of dexamethasone will cause a decreased level of cortisol in a normal pet; however, in a pet with Cushing's disease, there is minimal or no decrease in cortisol level. Other diseases can suppress cortisol production, so it is important to rule these out prior to dexamethasone testing. Knowing the type of Cushing's disease your pet has can guide treatment decisions and offers a more defined prognosis.
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Dexmedetomidine is a sedative/tranquilizer used primarily in cats and dogs as a pre-medication injection for anesthesia or for chemical restraint. It is also used orally in dogs for short-term anxiety management. The most common side effect is a low heart rate. Dexmedetomidine should not be used in patients with severe heart liver or kidney disease. It should be used cautiously in young, old, or weak animals. Consult your veterinary office immediately if you suspect a negative reaction or overdose.
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Dextromethorphan is given by mouth and is used off label to treat compulsive behaviors and occasionally used to treat cough. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, sleepiness, drooling or anxiousness. Do not use in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.
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Dextromethorphan + Guaifenesin is given by mouth as a tablet and is used off label to reduce cough in dogs and cats or to treat compulsive behavior. Side effects are uncommon, but serious adverse reactions associated with this drug may occur without warning. Contact your veterinarian if you notice anything out of the ordinary.
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Testing for diabetes includes confirming hyperglycemia and glucosuria while looking for other conditions by taking a complete blood count (anemia, infection), biochemistry profile (hepatic disease, pancreatitis), and a urinalysis (urinary tract infection). Monitoring includes regular glucose curves and additional exams and testing based on the pet owner's monitoring of their dog's clinical signs at home. Urine glucose testing and fructosamine are sometimes used in diabetic monitoring and urine testing for infection may be recommended.
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Diabetes insipidus results in excessive drinking and urination. As many conditions cause these signs, a number of diagnostic tests including bloodwork and urinalysis need to be performed to rule out other causes. After more common causes are ruled out, a modified water deprivation test can confirm disease and an MRI or therapeutic trial can be performed. Diabetes insipidus results from reduced production of ADH from the brain or reduced sensitivity to ADH in the kidney. Treatment depends on the cause of the disease either replacing the lack of ADH with a synthetic replacement or using a hydrochlorothiazide and a low salt diet to decrease urine production.
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Diabetes is an inability of the body to regulate blood sugar caused by an abnormality of the pancreas. It causes increased thirst, urination, appetite, and weight loss. Most dogs have type 1 diabetes, caused by total or near destruction of the insulin-producing cells, and insulin injections are required for treatment. Diabetes is diagnosed by measuring increased levels of glucose in the urine and blood. Diabetes treatment includes insulin injections and dietary manipulation with regular blood sugar monitoring. Financial costs can be high during the regulation period, or if a complication arises, and twice-daily insulin injections are a lifelong commitment.
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Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body's response to the injections needs to be regularly monitored using an at-home glucometer or continuous glucose monitoring system. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet.
